Cathepsin D coexists with renin in the secretory granules of juxtaglomerular epithelioid cells.

Autor: Taugner, R., Yokota, S., Bührle, C., Hackenthal, E.
Zdroj: Histochemistry; 1986, Vol. 84 Issue 1, p19-22, 4p
Abstrakt: Mature juxtaglomerular epithelioid cell secretory granules of the rat exhibit both renin-and cathepsin D-like immunoreactivity. On the basis of the coexistence with renin at a pH which, according to previous experiments, is probably in the range of that in lysosomes, cathepsin D is suggested to be involved in the regulation of the granular renin stores available for secretion. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index