Autor: |
Chalevelakis, George, Karatapanis, Stilianos, Yalouris, Athan, Thalassinos, Nick, Pallikaris, George, Anastasiou, Costas, Raptis, Sotos |
Zdroj: |
Acta Diabetologica Latina; 1987, Vol. 24 Issue 3, p249-253, 5p |
Abstrakt: |
Glycated fractions of hemoglobin F and A (F, A) were measured simultaneously in cord and maternal blood, respectively, in 109 normal women at delivery using an isoelectric focusing, method in polyacrylamide gel plates. Cord blood hemoglobin F values (mean ± SD) were 5.92±1.09% and maternal blood hemoglobin A values were 6.51±0.92%. The difference was statistically highly significant (p<0.001) and their values were also significantly correlated (p<0.001). Moreover, both values were also well correlated with those of maternal blood glucose (p<0.01), actual birth weight (p<0.01) and birth weight ratio (p<0.01). It is concluded that hemoglobin F can be successfully separated and measured by isoelectric focusing. However HbF estimation seems to have no obvious advantage against the maternal HbA measurement as an index of fetal exposure to glucose during the last weeks of pregnancy. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
|