Echocardiographic assessment of cardiac function and morphology in patients with generalised lipodystrophy.

Autor: Bjørnstad, P., Semb, B., Trygstad, O., Seip, M., Bjørnstad, P G, Semb, B K
Zdroj: European Journal of Pediatrics; 1985, Vol. 144 Issue 4, p355-359, 5p
Abstrakt: Because cardiomegaly has been observed in lipodystrophic patients we studied cardiac morphology and function with one- and two-dimensional echocardiography in addition to general cardiologic examination in a series of seven patients. Muscular hypertrophy with increased chamber size and myocardial indentations were found. Two patients had asymmetrical septal hypertrophy (ASH), and two patients demonstrated systolic anterior movement (SAM) of the mitral valve. Wall motion analysis showed anomalities in four patients during contraction, in three during the early relaxation phase. Since pathological findings, probably increasing with age, were made in the majority of the patients, these findings add an additional unfavourable aspect to the syndrome. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index