Osteogenic sarcoma complicating osteogenesis imperfecta tarda.

Autor: Lasson, U., Harms, D., Wiedemann, H.
Zdroj: European Journal of Pediatrics; 1978, Vol. 129 Issue 3, p215-218, 4p
Abstrakt: We describe the case history of a 13 years old boy who developed osteogenic sarcoma of the left thigh, six years after diagnosis of osteogenesis imperfecta tarda with a positive family history. Only four other patients with this disease combination are reported in the literature. Preoperative treatment with high-dose Methotrexate caused marked tumor regression, as shown at examination of amputation material. The inter-relationships between the two disorders are discussed and the literature is briefly reviewed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index