Sorption kinetics in haemoperfusion columns. Part 1: estimation of mass-transfer parameters.

Autor:	Radcliffe, D., Gaylor, J., Radcliffe, D F, Gaylor, J D
Předmět:	ACETAMINOPHEN ADSORPTION (Chemistry) COMPARATIVE studies CREATININE DYNAMICS HEMOPERFUSION MATHEMATICAL models RESEARCH methodology MEDICAL cooperation RESEARCH SALICYLATES THEORY EVALUATION research PHENOBARBITAL
Zdroj:	Medical & Biological Engineering & Computing; 1981, Vol. 19 Issue 5, p617-626, 10p
Abstrakt:	The in vitro measurement of adsorption isotherms and intraparticle diffusivities for three types of activated carbon and four exogenous and endogenous toxins is described. Complications due to the chemical breakdown of creatinine and paracetamol in the presence of activated carbon are discussed. Three methods are compared for the estimation of intraparticle diffusivity from the kinetic data. The simplest method is also used to reinterpret literature data comparing diffusivity values using plasma or HSA solution as opposed to buffer as the solvent. The adsorption isotherms and intraparticle diffusivities comprise the fundamental data used to validate the mass transfer model of a haemoperfusion column developed in Part 2. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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