Surface energetics analysis of artificial blood substitutes.

Autor: Kaelble, D., Moacanin, J., Kaelble, D H
Předmět:
Zdroj: Medical & Biological Engineering & Computing; 1979, Vol. 17 Issue 5, p593-601, 9p
Abstrakt: The surface and interfacial tensions for fluorocarbon aqueous emulsions used in artificial blood substitutes are evaluated over a wide range of surfactant concentrations. The surface tension of the nonionic surfactant in water is directly correlated to the interfacial tension between aqueous and fluorocarbon phases by a surface energetics model of isolated dispersion and polar contributions to interfactial work of adhesion and interfacial tension. This study shows that the polymeric surfactant which is an A-B-A triblock copolymer, where A is polyethylene oxide and B is polypropylene oxide, displays prominent surface and interfacial tension transitions at c=1×10 and c=0·10 weight fraction detergent in water. The c=10 transition is shown to produce a prominent change in the extensibility of the fluorocarbon to water interface and formation of a strong interfacial film that enhances emulsion stabilisation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index