| Autor: |
Griffiths, D., Mastrigt, R., Duyl, W., Coolsaet, B., Griffiths, D J, van Mastrigt, R, van Duyl, W A, Coolsaet, B L |
| Zdroj: |
Medical & Biological Engineering & Computing; 1979, Vol. 17 Issue 3, p281-290, 10p |
| Abstrakt: |
Strips of pig bladder have been maximally stimulated in vitro at 37°C via electrodes placed in the muscle, in order, particularly, to measure the dependence of the resulting active force on the velocity of shortening and on length changes. The active isometric force and the passive viscoelastic force are approximately, but not precisely, additive. The active isometric force, like the steady (equilibrium) passive force, is a function of the extension of the strip above its rest length, which is increased after subjection to a high passive force. The steady passive force increases quasiexponentially with this extension, of which it is therefore a measure. The active isometric force F increases approximately linearly with the extension until it approaches a maximum in the region where it and the steady passive force are comparable in size. The maximum is partly obscured by rest-length changes. The dependence of the active force F on the speed of shortening of the strip has been measured in a new way, with a correction for passive viscoelastic effects. For a given strip the ratio F/F is, approximately, a function of the contraction velocity only. The function is similar to that of the classical Hill equation but not identical, possibly for geometrical reasons. The results imply that a velocity parameter v, analogous to Hill's parameter b, is approximately constant for each strip, independent of changes of length and rest length. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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