| Autor: |
Kun, Yang, Chuan-lin, Mei, Qi, Zhou, Yu-fang, Jia, Chen-gao, Yu |
| Zdroj: |
Acta Academiae Medicinae Wuhan; 1986, Vol. 6 Issue 1, p48-52, 5p |
| Abstrakt: |
Heat stroke model was made under artificial hot environment in 26 mongrel dogs, and hemodynamic alterations and their mechanism were investigated. When the rectal temperature rose above 41°C the stroke volume (SV) and cardiac output (CO) significantly decreased. The central venous pressure (CVP) declined at first, but increased later and rose above the control value at 43°C. The mean arterial pressure (MAP) began to decrease at 41°C, and decreased by 25.7 % ( P < 0.01) at 42.5°C comparison with the control value. MAP dropped dramatically (68.4 %) at 43°C. Besides, the serum concentration of potassium increased by 6.1±1.6 mg ( P < 0.01) in comparison with the control value. Naloxone (0.1-0.3 mg/kg) was injected i.v. at 40. 5°C of rectal temperature. SV and CO increased markedly at 41°C and 42 °C. CVP declined significantly, and MAP showed elevation at 41°C. These findings suggested that the circulatory failure during heat stroke might be related to the increased β-endorphin release from the anterior pituitary gland and the increase of serum potassium concentration. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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