Influence of local injection of 5,7-DHT and 6-OH-DA into the neocortex on learning and exploratory behavior of rats in the open field.

Autor: Ismailova, Kh., Gasanov, G., Semenova, T., Bobkova, N., Nesterova, I., Gromova, E.
Zdroj: Neuroscience & Behavioral Physiology; 1990, Vol. 20 Issue 6, p493-499, 7p
Abstrakt: The features of the exploratory behavior in the open field, of the learning of a conditioned-reflex food-procuring reaction, and of the shift in the level of biogenic amines of the brain was studied in Wistar rats with local injections of the specific neurotoxins 6-hydroxydopamine (6-OH-DA) and 5,7-dihydroxytryptamine (5,7-DHT). It was shown that damage to the structure of the serotoninergic or catecholaminergic systems of the frontal cortex and hippocampus caused by local injection of 6-OH-DA and 5,7-DHT into the neocortex is accompanied by multidirectional changes in the exploratory behavior and learning of the animals. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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