| Abstrakt: |
Photic stimulation evokes a variety of epileptic discharges, including bilaterally synchronous spike-wave complexes at 3/sec, characteristic of myoclonic epilepsy. Microelectrode investigations have shown that epileptic unit activity is caused by chronic plastic changes in the synapses of cortical neurons developing in response to a strong flow of afferent impulses from the visual receptor. The relation of such factors as neuronal adaptation, depolarization inactivation, and the effect of activation of high-threshold inhibitory structures on the development of photogenic epilepsy are examined. Comparable investigations with stimulation of the auditory system and the vagus nerve point to increased flow of afferent impulses as an etiological and pathogenetic factor in epilepsy. [ABSTRACT FROM AUTHOR] |
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