| Autor: |
Grimmer, G., Brune, H., Dettbarn, G., Heinrich, U., Jacob, J., Mohtashamipur, E., Norpoth, K., Pott, F., Wenzel-Hartung, R. |
| Zdroj: |
Archives of Toxicology; Dec1988, Vol. 62 Issue 6, p401-405, 5p |
| Abstrakt: |
The urinary and faecal excretion of chrysene and its phenolic metabolites after oral, intraperitoneal, intratracheal, and intrapulmonary administration to rats have been studied by means of gas chromatography/mass spectrometry. The metabolite profile was found to depend on the mode of excretion and on the route of administration. In all cases the oxidation of chrysene in the 1,2- or 3,4-position predominates, whereas oxidation in the 5,6-position (K-region) seems be a minor pathway. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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