| Autor: |
Lauharanta, Jorma, Juvakoski, Timo, Kanerva, Lasse, Lassus, Allan |
| Zdroj: |
Archives of Dermatological Research; Jun1982, Vol. 273 Issue 1/2, p111-114, 4p |
| Abstrakt: |
Micronized 8-methoxypsoralen (8-MOP), with a smaller crystal size, produced significantly higher serum level profiles than nonmicronized 8-MOP. Furthermore, the absorption of the micronized drug was more rapid, resulting in peak serum levels within 1 h in 75% of the patients. Our blister fluid studies suggest, however, that reduction of the photosensitizer concentration is slower in skin than in serum. This implies that despite markedly reduced 8-MOP serum level after 2 h the skin remains sufficiently sensitized up to that point of time. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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