Autor: |
Matissek, Reinhard, Nagorka, Regine, Daase, Margit, Wengatz, Ingrid |
Zdroj: |
Fresenius' Zeitschrift für Analytische Chemie; 1989, Vol. 333 Issue 8, p806-809, 4p |
Abstrakt: |
Following part I which describes a high-performance liquid Chromatographic determination of methyliso-thiazolones after pre-column derivatization, part II presents a method based on it, for isolation and quantification of these preservatives in cosmetic preparations, especially those with emulsion-like bases. The emulsion is destroyed by extraction in a two-phase-system with simultaneous conversion of the methylisothiazolones. Most of the matrix constituents stay in the organic phase because of their apolar character whereas the highly polar derivatives enter the aqueous phase. Sodium nicotinate is suitable for quantification by the method of internal standard. The recoveries of both methylisothiazolones lie within 90%. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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