Differences between the neuronal handling of H-7- and H-7,8-(−)noradrenaline: implications for the release of the labelled neurotransmitter by nerve stimulation.

Autor: Henseling, M.
Zdroj: Naunyn-Schmiedeberg's Archives of Pharmacology; 1987, Vol. 335 Issue 2, p129-135, 7p
Abstrakt: Neighbouring rabbit aortic strips were exposed to a tracer concentration of H-7- or H-7,8-(−)noradrena-line (bearing 30-35% of its label in position 8) and to 0.5 μmol/l unlabelled (−)noradrenaline for 60 min and then washed in amine-free Krebs solution. Catechol-O-methyl transferase and extraneuronal amine uptake were inhibited throughout. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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