| Autor: |
Göthert, M., Hentrich, F. |
| Zdroj: |
Naunyn-Schmiedeberg's Archives of Pharmacology; 1984, Vol. 328 Issue 2, p127-134, 8p |
| Abstrakt: |
Strips of the rabbit pulmonary artery preincubated with H-noradrenaline were superfused with physiological salt solution containing cocaine, corticosterone and propranolol. Basal tritium efflux and electrically evoked tritium everflow were determined. It is concluded that the sympathetic nerves of the rabbit pulmonary artery appear to be endowed with an adenylate cyclase. cAMP is probably involved in the regulation of action potential-induced noradrenaline release, but does not play a crucial role for the initiation of the release mechanism itself. The data are compatible with (but do not prove) the involvement of an adenylate cyclase in the facilitatory effect of ACTH. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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