Specific H-imipramine binding in human platelets.

Autor: Langer, S., Briley, M., Raisman, Rita, Henry, J.-F., Morselli, P.
Zdroj: Naunyn-Schmiedeberg's Archives of Pharmacology; 1980, Vol. 313 Issue 3, p189-194, 6p
Abstrakt: Human platelets have been shown to possess high-affinity binding sites for H-imipramine. These binding sites have a similar affinity and drug specificity to those already described in rat brain. The platelets from healthy volunteers show no difference in H-imipramine binding between the sexes but there is a decrease in maximal H-imipramine binding with increasing age of the donor. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index