| Autor: |
Schaper, Wolfgang, Xhonneux, Raymond, Jageneau, Anton |
| Zdroj: |
Naunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie; 1965, Vol. 252 Issue 1, p1-8, 8p |
| Abstrakt: |
Lidoflazine, a new and very longacting coronary vasodilator was given to 18 dogs with a chronically developing stenosis and occlusion of the circumflex coronary artery for 4 and 6 weeks respectively. 18 other dogs with chronically developing stenoses leading to occlusion of the circumflex artery were used as controls. Lidoflazine in a dosis of 20 mg/kg/day increased the speed of development of the collateral circulation and prohibited symptoms of permanent cardiac hypoxia. Permanent myocardial hypoxia, caused by a higher degree of physical activity in a group of 'freely exercising' dogs produced the same favorable effects on the canine coronary collateral circulation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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