Synthesis and study of (2 S,4 S)-4-arylamino-2-carboxy-5-pyrrolidones.

Autor: Krasnov, V., Nizova, I., Sinitsyna, T., Avdyukova, N.
Zdroj: Russian Chemical Bulletin; 1993, Vol. 42 Issue 12, p2001-2004, 4p
Abstrakt: (2 S,4 S)-4-Arylamino-2-carboxy-5-pyrrolidones were prepared by hydrolysis of dimethyl (2 S,4 S)-4-arylamino-N-phthaloylglutamates. The protonation constants of the arylamino group in the synthesized compounds were determined. The pyrrolidone ring is stable in acidic or neutral solutions. The relative stability of the pyrrolidone ring in alkaline solutions was studied by IR spectroscopy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index