| Autor: |
Treilhou-Lahille, F., Lasmoles, F., Taboulet, J., Barlet, J., Milhaud, G., Moukhtar, M. |
| Zdroj: |
Cell & Tissue Research; 1984, Vol. 235 Issue 2, p439-448, 10p |
| Abstrakt: |
The ultimobranchial gland (UBG) of birds is particularly rich in calcitonin, the hypocalcaemic hypophosphataemic hormone, that is secreted by the C-cells of the mammalian thyroid. The principal cells of the UBG have a striking resemblance with the mammalian C-cells, i.e., they possess small intracytoplasmic dense-core secretory granules, 150-300 nm in diameter. The gland also contains a second, morphologically distinct, endocrine cell type with larger granules, 500-800 nm in diameter. A sensitive immunocytochemical reaction was developed with the use of antibodies against salmon calcitonin. By means of this technique the presence of calcitonin-immunoreactive molecules was demonstrated in both secretory cell types of the UB gland of the chicken. This gland can thus be considered as a homogeneous calcitonin-producing tissue. Whether the secretory products are identical is discussed and differences in the secretory pathways are suggested. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink