Ultrastructural changes in the rat carotid body in severe haemorrhagia.

Autor: Korkala, Olli, Waris, Timo
Zdroj: Cell & Tissue Research; 1975, Vol. 158 Issue 3, p355-362, 8p
Abstrakt: Rat carotid bodies were studied electron microscopically after short-term severe hypovolaemia, which is known to induce a marked chemoreceptor activation in the carotid body. Altogether 84 nerve-endings in the hypovolaemic rats' carotid bodies and 91 nerve-endings in the control carotid bodies were investigated. An increased accumulation of the glomus cell granular vesicles near the synaptic specializations of the nerve-endings was observed after hypovolaemia. Moreover, a statistically significant increase in the contacts between the nerve-ending synaptic specializations and the glomus cell granular vesicles was observed after hypovolaemia. A suggestion was made that the glomus cells might act as modulating, probably inhibitory, interneurones, whose catecholamines are responsible for the inhibition. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index