Enantiomerically selective metal complex catalysis. 7. Asymmetric hydrosilylation of imines and oximes on the catalyst [Rh(COD)Cl]/(S)-phephos.

Autor: Zhorov, E., Pavlov, V., Fedotova, O., Shvedov, V., Mistryukov, É., Platonov, D., Gorshkova, L., Klabunovskii, E.
Zdroj: Bulletin of the Academy of Sciences of The USSR, Division of Chemical Science; 1991, Vol. 40 Issue 4, p763-766, 4p
Abstrakt: Asymmetric hydrosilylation of acetophenoxime and cyclic and acyclic imines (with subsequent hydrolysis to amines) was investigated using as catalyst a rhodium complex with the chiral phosphinamino ligand (S)-Phephos. With this method the chiral analog of the antidepressant Pyrazidol was synthesized with an optical yield of 73%. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index