| Autor: |
Porwit, A., Panayotides, P., Mansson, E., Ösby, E., Hast, R., Reizenstein, P. |
| Zdroj: |
Blut: Zeitschrift für die Gesamte Blutforschung; 1987, Vol. 54 Issue 2, p73-78, 6p |
| Abstrakt: |
Cyclosporine A (CyA) treatment of 4 patients with severe aplastic anemia, who were ineligible for bone marrow transplantation, was carried out for periods of between 12 weeks to 20 months. A normalization of Hb and bone marrow, together with a marked improvement in WBC and platelet counts, were observed in only one of these four patients. The remission was maintained for 20 months under continuous treatment. A relapse occurred only when the patient himself interrupted treatment. No serious side effects were observed with CyA doses of 4-10 mg/kg/daily and blood concentrations of 200-400 ng/ml. No significant changes in T helper/T suppressor ratios were noted during the course of CyA treatment. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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