Retrospective Comparison of Laparoscopic Partial Nephrectomy Versus Laparoscopic Renal Cryoablation for Small (<3.5 cm) Cortical Renal Masses.

Autor: Haramis, Georgios, Graversen, Joseph A., Mues, Adam C., Korets, Ruslan, Rosales, Juan Carlos, Okhunov, Zhamshid, Badani, Ketan K., Gupta, Mantu, Landman, Jaime
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Zdroj: Journal of Laparoendoscopic & Advanced Surgical Techniques; Apr2012, Vol. 22 Issue 2, p152-157, 6p, 2 Charts
Abstrakt: Objective: We compared perioperative and short-term outcomes of renal laparoscopic partial nephrectomy (LPN) and laparoscopic cryoablation (LCA) in patients with small (<3.5 cm) renal cortical neoplasms. Methods: A retrospective analysis from our prospectively established database was performed. We identified 92 patients with 95 lesions treated with LPN and 75 patients with 91 lesions treated with LCA. Results: The LPN and LCA groups were comparable in mean tumor size and preoperative and postoperative creatinine level ( P=.495, P=.953, and P=.101) respectively. Patients undergoing LPN were younger in age (58.8 versus 69.2 years, P<.001), had a higher mean estimated blood loss (168.4 versus 66 mL, P=.005), and had a prolonged mean operative time (151.6 versus 128.6 minutes, P=.01). Six complications occurred in the LCA group and 11 in the LPN group. The median follow-up time was 21.8 months for LPN and 14 months for LCA ( P<.001). Two recurrences were detected in the LCA group, and 1 recurrence was reported after LPN. Conclusions: In the treatment of small renal cortical neoplasms with short-term follow-up, LPN and LCA seem to be equally effective. LCA offers decreased blood loss, shorter operative time, and less morbidity. Longer follow-up is required to establish oncologic efficacy. [ABSTRACT FROM AUTHOR]
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