| Autor: |
Gachályi, B., Káldor, A., Szeberényi, Sz. |
| Zdroj: |
European Journal of Clinical Pharmacology; 1978, Vol. 13 Issue 4, p299-302, 4p |
| Abstrakt: |
The enzyme inducing effect of m-trifluoromethyl-α-ethylbenzhydrol (RGH-3332) has been studied in man, rat and mouse. In man, RGH-3332 decreased the half-life of antipyrine and tolbutamide and increased d-glucaric acid excretion. In rat and mouse the half-life of antipyrine was shortened. It was concluded that in all three species man, rat and mouse the liver microsomal drug metabolizing enzyme system was induced by RGH-3332. No side-effects were found on treatment with RGH-3332. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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