| Autor: |
Giesecke, Ulrich, Bierbaum, Gabriele, Rudde, Heinz, Spohn, Uwe, Wandrey, Christian |
| Zdroj: |
Applied Microbiology & Biotechnology; 1991, Vol. 35 Issue 6, p720-724, 5p |
| Abstrakt: |
A production method for alkaline serine protease with Bacillus licheniformis in a synthetic medium was developed. Employing closed-loop control of oxygen, nitrogen and carbon source the pO was held at 5%, the ammonium concentration kept below 1 m M and the glycerol concentration was maintained between 20 and 100 m M. Protease production was monitored by flow injection analysis. Thus, in a fed-batch procedure production could be increased 4.6-fold in comparison to an uncontrolled batch process. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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