Persistent postural hypotension due to guanacline.

Autor: Dawborn, J., Doyle, A., Ebringer, A., Howqua, June, Jerums, G., Johnston, C., Mashford, M., Parkin, J.
Zdroj: Pharmacologia Clinica; 1969, Vol. 2 Issue 1, p1-5, 5p
Abstrakt: Case histories of five patients are presented who developed severe postural hypotension after being treated with guanacline. The postural hypotension did not develop until treatment had been given for 3-4 months and has persisted following withdrawal of guanacline for 12-15 months. It is suggested that this drug causes irreversible depletion of noradrenaline stores in adrenergic nerve terminals in some patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index