| Autor: |
Reynolds, John, Pavlovitch, H., Balsan, Sonia |
| Zdroj: |
Calcified Tissue Research; 1976, Vol. 21 Issue 12, p207-212, 6p |
| Abstrakt: |
Mice, 1 week old, prelabelled withCa, were either thyroparathyroidectomised or sham-operated; 1 day later half of the mice of each group were injected with 1,25-dihydroxycholecalciferol (5 ng/g), and 20 h later all the mice were killed. Bone resorption in explants was then measured by an in vivo/in vitro technique previously published; compared with untreated mice it was found that 1,25-dihydroxycholecalciferol had increased resorption irrespective of whether the mice had been thyroparathyroidectomised or not. These data suggest that 1,25-dihydroxycholecalciferol is able to increase bone resorption independently of parathyroid hormone. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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