Substituierte 3-Amino-thiophene und 3-Amino-selenophene aus β-Chlor-α-cyan-zimtsäurenitril.

Autor: Gewald, Karl, Hain, Ute
Zdroj: Chemical Monthly / Monatshefte für Chemie; 1992, Vol. 123 Issue 5, p455-459, 5p
Abstrakt: β-Chloro-α-cyano-cinnamonitrile (1) reacts in one step with α-oxo-thioles 3 or successively with sodium sulphide and α-chlorocarbonyl compounds 4 to form the 5-substituted 4-amino-2-phenyl-thiophene-3-carbonitriles 5. Analogously, the successive reactions of β-chloro cinnamonitrile 1 with sodium selenide - produced in situ from selene and sodium boronhydride - and α-chlorocarbonyl compounds 4 yields the 5-substituted 4-amino-2-phenyl-selenophene-3-carbonitriles 6. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index