Spontaneous osteo-arthritis of the knee-joint in C57BL mice receiving chronic oral treatment with NSAID's or prednisone.

Autor: Pataki, A., Graf, H., Witzemann, E.
Zdroj: Agents & Actions; Mar1990, Vol. 29 Issue 3/4, p210-217, 8p
Abstrakt: In a statistically planned study based on quantitative radiography, treatment for 25-26 weeks with the 2 NSAIDs, diclofenac sodium, or indomethacin (both 0.5 and 1.5 mg/kg p.o. daily), or prednisone (6 mg/kg p.o.) had no influence on the progression of spontaneous osteo-arthritis of the knee-joint of the C57BL mouse, by comparison with placebo-treated controls. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index