Histamine secretion from mast cells stimulated with somatostatin.

Autor: Kassessinoff, T., Pearce, F.
Zdroj: Agents & Actions; May1988, Vol. 23 Issue 3/4, p211-213, 3p
Abstrakt: Histamine release from isolated mast cells stimulated with somatostatin resembled that induced by other basic agents. The process was rapid, independent of added calcium or phospholipids, non-cytotoxic, species and tissue specific, not mediated through cell-fixed antibodies or glucoreceptors, and inhibited by antagonists of the polyamine receptor. Somatostatin and other polycations may then act through a common receptor or binding site on the mast cell membrane. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index