| Autor: |
Mikulíková, Daniela, Tranavský, Karel |
| Zdroj: |
Agents & Actions; Sep1980, Vol. 10 Issue 4, p374-377, 4p |
| Abstrakt: |
In order to study the influence of levamisole on lysosomal enzyme release, human polymorphonuclear (PMN) leukocytes were incubated with 0.5 mg/ml monosodium urate crystals. The release of neutral proteinase, beta glucuronidase, myeloperoxidase and lactic dehydrogenase as cytoplasmatic marker was measured. Preincubation of PMN with various concentrations of levamisole lasting 1h resulted in a decrease of all enzymes released. Intracellular levels of both cyclic nucleotides-cAMP and cGMP-rose in PMN preincubated with levamisole, in comparison with untreated cells. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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