| Autor: |
Rassaert, Charles, Dipasquale, Gene, O'Donoghue, Sandra |
| Zdroj: |
Agents & Actions; May1975, Vol. 5 Issue 2, p128-132, 5p |
| Abstrakt: |
A new anti-inflammatory assay is described, utilizing a subcutaneously implanted elongated section of cotton twine to induce granuloma in rats. The cotton twine irritant is easily introduced under the abdominal skin and after seven days a well formed granuloma is established. The procedure works effectively for both steroidal and nonsteroidal anti-inflammatory drug evaluation. Consistency of the cotton twine eliminates individual weighing of each section and uniformity in compactness affords reproducible results. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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