| Autor: |
Berglund, J., Haldén, E., Jakobson, S., Svensson, J., Berglund, J E, Haldén, E |
| Zdroj: |
Intensive Care Medicine; May1994, Vol. 20 Issue 5, p360-364, 5p |
| Abstrakt: |
Objective: This study was designed to see if humorally mediated negative inotropism contributes to the cardiac output (CO) depression seen during positive end-expiratory pressure (PEEP) ventilation.Design: 8 pairs of piglets were used and a combined blood circulation was established between the two animals in each pair. One animal was ventilated with a PEEP of 15 cmH20 (donor) and the other was ventilated without PEEP (recipient).Measurement and Results: CO and stroke volume deteriorated in the donors by 32% and 44%, respectively, while no change was seen in the recipients.Conclusion: As humorally mediated negative inotropism during PEEP ventilation has earlier been demonstrated in dogs, the results suggest that this mechanism might be species-dependent. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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