| Autor: |
Karrer, K., Denck, H., Karnicka-Mlodkowska, H., Drings, P., Orel, J., Salzer, G., Thermann, M., Lattuneddu, A., Sun, Y., Hata, E., Berkarda, B., Liao, M., Bruno, F., Rothmund, J., Osada, H. |
| Zdroj: |
Medical Oncology & Tumor Pharmacotherapy; Jun1989, Vol. 6 Issue 2, p143-149, 7p |
| Abstrakt: |
For the optimisation of the therapy for small cell bronchial carcinomas (SCLC), surgery is used to eliminate the primary tumor and its regional lymph nodes and chemo- and radiotherapy for the general treatment of micrometastasis. After patho-histological examination of the operation specimen, randomization for two arms is performed for a standard chemotherapy (CAV) or a sequential chemotherapy using three different drug combinations. Thereafter all disease-free patients receive prophylactic cranial irradiation (PCI). Preliminary evaluations in December 1987, of 112 patients from 19 cooperating departments show that the survival rate projected for 2 yr of 43 patients at stage pT1-3 N0 M0 is 76%, of 43 patients at stage pT1-3 N1 M0 it is 63% and of 26 patients at stage pT1-3 N2 M0 it is 38%. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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