A first-generation linkage disequilibrium map of human chromosome 22.

Autor: Dawson, Elisabeth, Abecasis, Goncalo R., Bumpstead, Suzannah, Chen, Yuan, Hunt, Sarah, Beare, David M., Pabial, Jagjit, Dibling, Thomas, Tinsley, Emma, Kirby, Susan, Carter, David, Papaspyridonos, Marianna, Livingstone, Simon, Ganske, Rocky, Lohmussaar, Elin, Zernant, Jana, Tonisson, Neeme, Remm, Maido, Magi, Reedik
Předmět:
Zdroj: Nature; 8/1/2002, Vol. 418 Issue 6897, p544, 5p, 2 Diagrams
Abstrakt: Provides information on a study which demonstrated the feasibility of developing genome-wide maps of linkage disequilibrium (LD) along the complete sequence of human chromosome 22. Implication of DNA sequence variants in specific genes of the human genome; Correlation between high LD and low recombination frequency in the extant genetic map; Effect of characterizing the empirical patterns of LD across the genome.
Databáze: Complementary Index