Perceived stress in prodromal Huntington disease.
Autor: | Downing, Nancy, Smith, MeganM., Beglinger, LeighJ., Mills, James, Duff, Kevin, Rowe, KellyC., Epping, Eric, Paulsen, JaneS., the PREDICT-HD Investigators of the Huntington Study Group |
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Předmět: |
HUNTINGTON'S chorea diagnosis
ANALYSIS of covariance HUNTINGTON disease ANALYSIS of variance CHI-squared test MENTAL depression INTERVIEWING NEUROPSYCHOLOGICAL tests SENSORY perception PSYCHOLOGICAL tests RESEARCH funding SCALES (Weighing instruments) PSYCHOLOGICAL stress GENETIC testing SECONDARY analysis EFFECT sizes (Statistics) DESCRIPTIVE statistics PSYCHOLOGY GENETICS |
Zdroj: | Psychology & Health; Feb2012, Vol. 27 Issue 2, p196-209, 14p |
Abstrakt: | This study examines perceived stress and its relationship to depressive symptoms, life changes and functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity to HD diagnosis (far, mid, near) and compared with a non-gene-expanded comparison group. Persons in the mid group had the highest stress scores. A significant interaction between age and time since HD genetic testing was also found. Secondary analyses using data from a different data collection point and including a diagnosed group showed the highest stress scores in the diagnosed group. Possible explanations and implications are discussed. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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