| Abstrakt: |
Mixed ligand complexes of cis-[M(MetH)Cl] (M=Pd and Pt; MetH=methionine) with 2,4-disubstituted pyrimidines were prepared and characterised. The cis-[Pd(MetH)Cl] complex reacted with cytosine (2-hydroxy-4-aminopyrimidine), isocytosine (2-amino-4-hydroxypyrimidine) and thiocytosine (2-thio-4-amino-pyrimidine) to form ternary complexes. cis-[Pt(MetH)Cl] however reacted with cytosine, uracil (2,4-pyrimidine dione or 2,4-dihydroxypyrimidine) to yield the corresponding mixed ligand complexes. The primary ligand, methionine, binds to the metal ion through sulphur and amino nitrogen via a six membered chelate ring. The secondary ligands (substituted pyrimidines) bind to the Pd or Pt metal ion through the ring nitrogen (N), as monodentate ligand. Thiocytosine however acts as a bidentate ligand, coordinating to the metal ion through-SH and ring nitrogen (N). All complexes are 1∶1 electrolytes, except the thiocytosine complex, which is a 1∶2 electrolyte. [ABSTRACT FROM AUTHOR] |
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