| Autor: |
Eapen, Libni, Vachet, Mylene, Catton, Gordon, Danjoux, Cyril, McDermot, Rebecca, Nair, Bhavani, Girard, Andre, Genest, Paul, Stewart, David, Gerig, Lee |
| Zdroj: |
Journal of Neuro-Oncology; May1988, Vol. 6 Issue 1, p31-35, 5p |
| Abstrakt: |
A review of 43 patients with cerebral metastases, an unknown primary, and no other sites of metastases is presented. 27/43 (62.7%) had solitary metastases and 37.2% (16/43) had multiple metastases. Surgical treatment involved complete resection in 30.2%, subtotal resection in 37.2% and biopsy alone or no surgical procedure in the remainder. 39/43 patients underwent whole brain irradiation with the majority receiving 3000-4000 rads/10-20 fractions. Overall survival was 52% at six months and 20% at one year, and was significantly better in patients with solitary as opposed to multiple metastases (p < 0.03). A failure analysis including autopsy data demonstrates that (28/41) 68.3% of patients died of progressive intracranial disease without extracerebral metastases. Implications for treatment strategies are discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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