| Autor: |
Snetkov, V., Nigmatullin, N., Nikol'skii, E., Magazanik, L. |
| Zdroj: |
Neurophysiology; Jul1989, Vol. 21 Issue 4, p339-346, 8p |
| Abstrakt: |
A mathematical model of the effects of open (ionic) channel blockers on generation of postsynaptic current at the neuromuscular junction is described. Quantitative aspects of simple blocking action are analyzed as well as criteria by which blockade of ionic channels may be discriminated from modification of their activation kinetics. Results of simulation are compared with experimental data. Some effects of channel-blocking substances following cholinesterase inhibition are examined. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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