| Autor: |
Lewin, Anita, Bos, Mary, Zusi, F., Nair, Xina, Whiting, Gary, Bouquin, Pamela, Tetrault, Geraldine, Carroll, F. |
| Zdroj: |
Pharmaceutical Research; Feb1994, Vol. 11 Issue 2, p192-200, 9p |
| Abstrakt: |
Evaluation of 13- cis-12-substituted analogues of retinoic acid in a series of dermatologic screens has revealed that structural modifications can lead to selectivity and specificity. An analogue, 11- cis,13- cis-12-hydroxymethylretinoic acid, δ-lactone, has been found to have good activity and to be devoid of topical and systemic toxicity. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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