PkpA, a novel Phycomyces blakesleeanus serine/threonine protein kinase.

Autor: Ruiz-Pérez, Victor, Murillo, Francisco, Torres-Martínez, Santiago
Zdroj: Current Genetics; Sep1995, Vol. 28 Issue 4, p309-316, 8p
Abstrakt: This work reports the cloning and sequencing of pkpA, a gene of the filamentous fungus Phycomyces blakesleeanus, whose expression seems to be coupled to vegetative growth. This gene encodes a putative serine/threonine-specific protein kinase, whose sequence is related to that of the yeast protein STE20, involved in pheromone-response pathways, and to a number of MAPK kinase proteins. However, detailed analysis of the kinase sequence suggests that PkpA is a novel serine/threonine protein kinase that probably participates as an intermediate in an intracellular system controlling nuclear proliferation in P. blakesleeanus. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index