| Autor: |
Nakao, Norio, Uchida, Hideo, Kamino, Keiji, Nishimura, Yukihiro, Ohishi, Hajime, Takayasu, Yukio, Nakamura, Hironobu, Kuroda, Chikazumi, Fujita, Makoto, Yoshioka, Hiroyasu, Ishida, Osamu |
| Zdroj: |
Cancer Chemotherapy & Pharmacology; Jan1992, Vol. 31 Issue 1, pS72-S76, 5p |
| Abstrakt: |
The effectiveness of Lipiodol (iodized oil) in transcatheter arterial embolization (TAE) of hepatocellular carcinoma (HCC) was retrospectively evaluated using statistical analysis. A total of 343 HCC patients who underwent TAE at 5 institutions between 1984 and 1989 were divided into 2 groups: the GS-TAE group underwent TAE with Gelfoam sponge alone, whereas the LP-TAE group was given Lipiodol (LP) immediately before GS-TAE. The statistical T value calculated for the LP-TAE group showed that the administration of LP, the tumor size, intrahepatic metastasis, portal vein infiltration, and serum total bilirubin and alpha-fetoprotein levels significantly ( P<0.01) affected the patients' survival. Both the cumulative survival determined using the Kaplan-Meier model and the cumulative hazard calculated using Cox's proportional hazard model differed significantly ( P<0.01) between the GS-TAE group and the LP-TAE group (log-rank test). These results confirmed the effectiveness of LP used in combination with Gelfoam sponge for TAE of HCC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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