Autor: |
Annenkov, V., Kruglova, V., Kazimirovskaya, V., Leshchuk, S., Moskvitina, L., Boiko, N., Anan'ev, V. |
Zdroj: |
Pharmaceutical Chemistry Journal; Jan1995, Vol. 29 Issue 1, p42-44, 3p |
Abstrakt: |
The physiological activity of the N-H acid 5-isopropenyltetrazole - 1-vinylpyrrolidone copolymers was studied. The copolymers were found to have anticoagulant properties, but unlike heparin, they act only on the initial stages of blood coagulation. The copolymers were discovered to have immunostimulating activity after immunization of mice with sheep erythrocytes. Investigation of the immunoadjuvant properties of the given compounds with respect to the surface antigen of the hepatitis B virus showed them to have an activity at the level of Freund's adjuvant. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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