| Autor: |
Parfenov, É., Smirnov, L. |
| Zdroj: |
Pharmaceutical Chemistry Journal; Sep1992, Vol. 26 Issue 9/10, p657-676, 20p |
| Abstrakt: |
Thus, increases in therapeutic effects can be achieved by various methods: by increasing ascorbic acid doses, by combing ascorbic acid with synergistic agents, and by using it as a chemoprotector against xenobiotics; the most effective way is by chemical modification. Increasing lipophilicity can widen the spectrum of biological activity in the desired direction, and substitution of the hydroxyl group or the carbon at position 2 prolongs the antioxidant activity of ascorbic acid and its associated pharmacological effects, as does complex formation (when the chemical structure of ascorbic acid is not changed), which increases the antioxidant activity - the most important prerequisite for its biological [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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