| Autor: |
Shvedov, V., Alekseev, V., Altukhova, L., Grinev, A. |
| Zdroj: |
Pharmaceutical Chemistry Journal; Dec1968, Vol. 2 Issue 12, p653-656, 4p |
| Abstrakt: |
1-Aryl-10-methylpyrazino(1,2-a)indoles are prepared by the condensation of ammonium acetate in acetic acid solution and the dibutyl acetals of 2-aroylindolyl-1-acetaldehydes which are formed by the reaction of the sodium derivatives of 2-aroyl-3-methylindoles with bromoacetaldehyde dibutyl acetal. 1-Aryl-1,2,3,4-tetrahydro-10-methylpyrazino(l,2-a)indoles are prepared by the reduction of the 1-aryl-10-methylpyrazinoindoles with sodium in alcohol. Furthermore, the synthesis of N-alkyl-dialkylamino derivatives of the 2-aroyl-3-methylindoles are carried out by the alkylation of the appropriate indoles with bisdiethylaminomethane and alkyldialkylamino chlorides. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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