Behavior of biliary phospholipids in intestinal lumen during fat digestion in rat.

Autor: Nalbone, G., Lairon, D., Lafont, H., Domingo, N., Hauton, J., Sarda, L.
Zdroj: Lipids; Oct1974, Vol. 9 Issue 10, p765-770, 6p
Abstrakt: The phospholipids present in the intestinal lumen of rats following ingestion of triglycerides are of biliary origin. They consist of lecithins accompanied by a small proportion of lysolecithins. Their behavior in comparison with the other lipid constituents of the intestinal content was studied by subjecting the latter to gel filtration on an agarose column in the presence of a solution of 6 mM sodium taurocholate in 0.1 M NaCl. Part of the phospholipids is present with the triglycerides and diglycerides in the emulsified phase excluded from the gel where pancreatic lipase and colipase also are found. The remainder is found in optically clear fractions containing fatty acids, monoglycerides, and bile salts. These fractions are eluted at 2.0 column volumes, while mixed fatty acids, monoglycerides, bile salts micelles emerge from the column at 2.4 column volumes in the same chromatographic conditions. This difference in behavior may be explained by the presence of biliary lecithins. This presence could have an important bearing upon the mucosal uptake of the lipolysis products of triglycerides. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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