Lung function in pulmonary sarcoidosis.

Autor: McCarthy, D., Sigurdson, M.
Zdroj: Irish Journal of Medical Science; Dec1978, Vol. 147 Issue 1, p413-419, 7p
Abstrakt: We measured lung volumes, maximum expiratory flow rates, gas exchange at rest and on exercise, and lung elastic recoil in 29 unselected subjects with pulmonary sarcoidosis. We grouped our patients according to the lung elastic recoil. Seventeen patients (59%) had normal lung elastic recoil, 9 patients (31%) had a restrictive defect and increased elastic recoil and 3 patients (10%) had diminished recoil and an obstructive ventilatory pattern of lung disease. Reduced airflow measurements were found in 6 patients (21%) with pulmonary sarcoidosis. Increased upstream resistance (RUS) accounted for the airflow decrement in 3 patients while reduced transpulmonary pressure was responsible in the remainder. The subjects with increased RUS had restrictive ventilatory pattern of lung dysfunction while the 3 patients with reduced flow and normal RUS had an obstructive pattern. The 3 patients with decreased airflow and normal upstream resistance were cigarette smokers. We conclude that reduced airflow is not uncommon in pulmonary sarcoidosis and may be due to primary disease of the airways or reduced lung elastic recoil. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index