| Autor: |
Shih, Wei-Jen, DeLand, Frank, Simmons, Guy, Coupal, John, Domstad, Peggy, Lee, Lu-Yuan |
| Zdroj: |
European Journal of Nuclear Medicine; Apr1986, Vol. 11 Issue 12, p498-501, 4p |
| Abstrakt: |
Pulmonary edema induced by injections of oleic acid was demonstrated using In-chloride lung/heart image in five anesthetized dogs. The anesthetized dogs were positioned under a gamma camera interfaced to a computer. After In-chloride IV injections, dynamic data were recorded at 1 frame/min before and after induced pulmonary edema. The computer generated the curve of the lung-to-heart activity ratio; the ratio rose from 0.5-0.6 at baseline to 0.85-1.5 at the end of the study in the dogs. At the end of each study, the removed lungs demonstrated edematous fluid, and a few red blood cells were seen in the alveoli. The results indicating pulmonary edema exhibited in the In-chloride lung-to-heart ratio obtained from a computerized gamma camera were compatable with the pathological results. Since In-chloride instantly binds to plasma transferrin, an excellent intravascular imaging agent, leakage of this tracer into alveoli indicates loss of membranous wall competence. Pulmonary edema, as in the adult respiratory distress syndrome, is sometimes difficult to diagnose; and this In-chloride lung-to-heart imaging technique may be potentially useful. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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