Preferential accumulation of C in human brain tumors after intravenous injection of C-1-pyruvate.

Autor: Tsukiyama, Takashi, Hara, Toshihiko, Iio, Masaaki, Kido, Goro, Tsubokawa, Takashi
Zdroj: European Journal of Nuclear Medicine; Sep1986, Vol. 12 Issue 5/6, p244-248, 5p
Abstrakt: Regional cerebral turnover of C following intravenous injection of C-1-pyruvate was investigated in 12 patients with brain tumors. The positron emission tomography (PET) image taken at 10-15 min after the injection always demonstrated a high concentration of C in tumor, and thus visualized precise tumor contours. This phenomenon was not influenced qualitatively by the variation of blood flow in the tumor. Brain edema associated with the tumor was not visualized. We conclude that the localization of brain tumors would be well determined by the PET scan, using C-1-pyruvate. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index