Immunoscintigraphy and distribution study of experimental tumours usingI-labelled anti-fibrinogen antibodies.

Autor: Švihovcová, P., Kopřivová, H., Glagoličová, A., Novák, F., Sůrová, H., Dienstbier, Z.
Zdroj: European Journal of Nuclear Medicine; Oct1984, Vol. 9 Issue 10, p478-481, 4p
Abstrakt: I-labelled antibodies to the fragment E of human fibrin, anti-rat fibrinogen, non-immune rabbit IgG andGa-citrate were used for scintigraphy and distribution studies in experimental tumours in rats. The best visualisation was achieved withI-labelled anti-rat fibrinogen antibodies at intervals longer than 48 h after administration. Tumour to tissue ratios found in distribution studies performed more than 48 h after administration were higher in most examined tissues when usingI-labelled antibodies than those obtained withGa-citrate. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index